'...instead of waking up every morning and shouting, "Somebody loves me!" you start looking around and thinking, "What do I want now? What's the next thing I need to be happy?" So... you look and you look, and you keep thinking you've found it, but nothing works. And the reason that nothing works is because... that hole in your heart that you're trying to fill... is already filled. You just forgot.'
"Desperate Housewives", series finale